Cnidoscolus aconitifolius leaf extract and ascorbate confer amelioration and protection against dimethyl nitrosamine-induced renal toxicity and testicular abnormalities in rats
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منابع مشابه
Cnidoscolus aconitifolius leaf extract protects against hepatic damage induced by chronic ethanol administration in Wistar rats.
AIMS This study focused on the possible protective effect of Cnidoscolus aconitifolius leaf extract (CA) against hepatic damage induced by chronic ethanol administration in rats. METHODS Male Wistar rats were distributed into seven groups of six rats each. The first group was the control, second group received 20% ethanol-only (7.9 g/kg), third and fourth groups were pre-treated with CA (100 ...
متن کاملAmelioration of carbon tetrachloride-induced hepatotoxicity and haemotoxicity by aqueous leaf extract of Cnidoscolus aconitifolius in rats.
This study was conducted to explore possible protective effect ofCnidoscolus aconitifolius (CA) leaf extract on carbon tetrachloride (CCl4)-induced hepatotoxicity and haemotoxicity in experimental animal models. Thirty six rats of six per group were used in this study. Group I received 10ml/kg normal saline as control. Group II-VI rats were administered with 1.25ml/kg body weight (bwt) of carbo...
متن کاملMethanolic extract of Cnidoscolus aconitifolius attenuates renal dysfunction induced by chronic ethanol administration in Wistar rats.
AIMS The present work studied the modulatory role of methanolic extract of Cnidoscolus aconitifolius leaf (MECA) in rat model of renal dysfunction induced by chronic ethanol administration. METHODS Forty-two male Wistar albino rats weighing between 170 and 180 g were distributed into seven groups of six animals each. Some groups were pretreated with MECA (100 and 200 mg/kg) or kolaviron (KV) ...
متن کاملSaussurea Costus Extract Has Anti-inflammatory, Antioxidant, and Hormonal Effects Against Testicular Toxicity Induced by Oxaliplatin in Male Albino Rats
Background: Testicular dysfunction is one of the common side effects that results from the treatment with oxaliplatin® as a chemotherapy drug, and pharmaceutical search for agents to relieve the side effects are underway. The current study explored the possible ameliorative and regenerative effects of Costus ethanolic extract against testicular degeneration in male rats induced by oxaliplatin. ...
متن کاملEfficiency of naringin against reproductive toxicity and testicular damages induced by bisphenol A in rats
Objective(s): Bisphenol A (BPA) as a synthetic compound is applied in many plastic industries. BPA has been reported to have endocrine-disrupting feature with cytotoxic effects. The study aimed to evaluate the efficiency of Naringin against testicular toxicity induced by BPA in adult rats.Materials and Methods: The animals were assigned into six groups of control, BPA-treated (50 mg/kg), BPA+Na...
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ژورنال
عنوان ژورنال: Toxicology Reports
سال: 2021
ISSN: 2214-7500
DOI: 10.1016/j.toxrep.2021.05.011